The big advantage of Unicode is the character compatibility between systems (PC, Mac), languages (international) and applications (word processing, layout programs, browsers, etc.). Requirements are Mac OS X (and Microsoft Office from version 2004) or Windows 2000/XP/Vista (and Office from version 2000). The new generation browsers (Firefox, Opera, Safari, etc.) are all Unicode-enabled.
For the easy handling of Unicode you need, besides a Unicode font, a keyboard layout which allows the input of the (non-Latin) special characters in an easy way.